郑玉新，必赢线路检测中心院长，博士，首席教授，博士生导师。国家杰出青年基金获得者，山东省泰山学者特聘教授。任中国毒理学会监事长、中国环境诱变剂学会副理事长、中国环境诱变剂学会生物标志物专业委员会主任委员。任国家环境与健康咨询委员会委员、IPCS/WHO危险度评价咨询委员会、WHO纳米健康工作组等国际组织咨询专家。担任《中华预防医学杂志》副主编以及《科学通报》等多个国际、国内学术期刊编委。曾任国家自然科学基金委第四届医学科学部专家咨询委员会委员、中国疾病预防控制中心职业卫生与中毒控制所副所长、WHO职业卫生合作中心（北京）主任、国家职业卫生标准委员会副主任委员等。获中华预防医学奖、“十一.五”国家科技计划执行突出贡献奖等奖项。曾主持完成的科研项目主要包括国家自然科学基金重点项目和面上项目、973项目、国家“十一.五、”、“十二.五”、“十三.五”科技支撑项目、卫生公益性行业科研专项重点项目以及国际合作项目等。主编和参编书籍6部，发表论文400余篇。培养博士和硕士研究生50余名。
一、主要研究方向
环境有害因素对健康影响的标志物及其转化应用
二、代表性科研成果
1.Junfeng (Jim) Zhang*#, Yuxin Zheng#, Roel Vermeulen#, Xing (Lucy) Liu, Yufei Dai, Wei Hu, Linchen He, Yan Lin, Dianzhi Ren, Huawei Duan, Yong Niu, Jun Xu, Wei Fu, Kees Meliefste, Baosen Zhou, Jufang Yang, Meng Ye, Xiaowei Jia, Tao Meng, Ping Bin, Bryan A. Bassig, H. Dean Hosgood III, Debra Silverman, Qing Lan, Nathaniel Rothman. Urinary Amino-PAHs in relation to diesel engine emissions and urinary mutagenicity. International Journal of Hygiene and Environmental Health, 2023, 253: 114223. doi: 10.1016/j.ijheh.2023.114223.
2.晋小婷，郑玉新*. 关注柴油机尾气的健康危害，加强职业防护. 环境与职业医学, 2023, 40(5), 487-490. doi: 10.11836/JEOM22450
3.Xin Li#, Jianzhong Zhang#, Mingyue Wang#, Chao Du, Wenjing Zhang, Yingying Jiang, Wanjun Zhang, Xinmin Jiang, Dunqiang Ren, Hongmei Wang, Xinru Zhang, Yuxin Zheng*, Jinglong Tang*. Pulmonary surfactant homeostasis dysfunction mediates multiwalled carbon nanotubes induced lung fibrosis via elevating surface tension. ACS Nano, 2023. doi:10.1021/acsnano.3c05956.
4.Mohammad L. Rahman*, Bryan A. Bassig, Yufei Dai, Wei Hu, Jason Y. Y. Wong*, Batel Blechter, H. Dean Hosgood, Danzhi Ren, Huawei Duan, Yong Niu, Jun Xu, Wei Fu, Kees Meliefste, Baosen Zhou, Jufang Yang, Meng Ye, Xiaowei Jia, Tao Meng, Ping Bin, Debra T. Silverman, Roel Vermeulen, Nathaniel Rothman, Yuxin Zheng*, Qing Lan. Proteomic analysis of serum in workers exposed to diesel engine exhaust. Environmental and Molecular Mutagenesis, 2022, 63:18-28. doi: 10.1002/em.22469.
5.Lizhu Ye#, Zhini He#, Daochuan Li#, Liping Chen, Shen Chen, Ping Guo, Dianke Yu, Lu Ma, Yong Niu, Huawei Duan, Xiumei Xing, Yongmei Xiao, Xiaowen Zeng, Qing Wang, Guanghui Dong, Michael Aschner, Yuxin Zheng*, Wen Chen*. CpG site-specific methylation as epi-biomarkers for the prediction of health risk in PAHs-exposed populations. Journal of Hazardous Materials, 2022, 431: 128538. doi: 10.1016/j.jhazmat.2022.128538.
6.戴宇飞, 郑玉新*. 中国职业卫生与职业病研究的进展. 中华疾病控制杂志, 2022, 26: 869-875. doi: 10.16462/j.cnki.zhjbkz.2022.08.001.
7.Zijian Xu#, Limei Shi#, Daochuan Li, Qincheng Wu, Ying Zhang, Mengyu Gao, Andong Ji, Qixiao Jiang, Rui Chen, Rong Zhang, Wen Chen, Yuxin Zheng*, Lianhua Cui*. Real ambient particulate matter-induced lipid metabolism disorder: Roles of peroxisome proliferators-activated receptor alpha. Ecotoxicology and Environmental Safety, 2022, 231: 113173. doi: 10.1016/j.ecoenv.2022.113173.
8.Yanting Li#, Teng Shi#, Xin Li, Huimin Sun, Xiaowen Xia, Xiaoya Ji, Jianzhong Zhang, Meike Liu, Yongfeng Lin, Rong Zhang, Yuxin Zheng*, Jinglong Tang*. Inhaled tire-wear microplastic particles induced pulmonary fibrotic injury via epithelial cytoskeleton rearrangement. Environment International, 2022, 164:107257. doi: 10.1016/j.envint.2022.107257.
9.Xiaoran Wei, Xiaowen Tang, Nan Liu, Yuansheng Liu, Ge Guan, Yi Liu, Xiaohan Wu, Yingjie Liu, Jingwen Wang, Hanqi Dong, Shengke Wang*, Yuxin Zheng*. PyCoCa:A quantifying tool of carbon content in airway macrophage for assessment the internal dose of particles. Science of the Total Environment, 2022, 851: 158103. doi: 10.1016/j.scitotenv.2022.158103.
10.Xiaowen Xia, Yuxin Zheng*, Xiaowen Tang, Nan Zhao, Bing Wang, Huan Lin, and Yongfeng Lin*. Nontarget identification of novel Per- and polyfluoroalkyl substances in cord blood samples. Environmental Science & Technology, 2022, 56: 17061-17069. doi: 10.1021/acs.est.2c04820.
11.Liu Hong, Li Jianyu, Ma Qianli, Tang Jinglong, Jiang Menghui, Cao Xue, Lin Li, Kong Nan, Yu Shanfa, Sood Akshay, Zheng Yuxin *, Leng Shuguang *, Han Wei*. Chronic exposure to diesel exhaust may cause small airway wall thickening without lumen 1142 narrowing: a quantitative computerized tomography study in Chinese diesel engine testers. Particle and fibre toxicology. 2021, 18(1):1-13.
12.Yu Tao, Zhang Xueyan, Li Shufei, Zhou Yumei,Li Bin, Wang Zhongxu, Dai Yufei, Adamson Sherleen Xuefu, Zheng YuXin*, Bin Ping*. Assessment of Benchmark Dose in BEAS-2B Cells by Evaluating the Cell Relative Viability with Particulates in Motorcycle Exhaust via the Air-liquid Interface Exposure. Biomedical and Environmental Sciences, 2021, 34(4), 272-281.
13.Wang Tao, Zhou Yunping, MS Yunsun, Zheng Yuxin*. Trends in Blood Lead Levels in the U.S. From 1999 to 2016. American Journal of Preventive Medicine, 60(4): 179-187.
14.Sai, Lin*, Qi, Xuejie, Yu, Gongchang, Zhang, Juan, Zheng, Yuxin*, Jia, Qiang*, Peng, Cheng. Dynamic assessing silica particle-induced pulmonary fibrosis and associated regulation of long non-coding RNA expression in Wistar rats. Genes and Environment, 2021,43(1), 1-12.
15.Jiang Qixiao, Xu Xiaohui, Ni Hao, Guo Yajie, Yua Junhua, Zheng Yuxin*. In Ovo Early-in-Life Inhalation Exposure to Gas/Aerosol with a Chicken Embryo Model. Methods in molecular biology, 2021, 2326: 197-201
16.Zhang Jianzhong, Ren Dunqiang, Cao Xue, Wang Tao, Geng Xue, Li Xin, Tang Jinglong, Leng Shuguang, Wang Hongmei, Zheng, Yuxin*. Ambient air pollutants and hospital visits for pneumonia: a case-crossover study in Qingdao, China. BMC public health, 2021, 21(1): 66
17.Hu Wei, Wang Yanhua, Wang Ting, Ji Qianpeng, Jia Qiang, Meng Tao, Zhang Zhihu, Li Yanbo, Chen Ru, Dai Yufei, Luan Yang, Sun Zhiwei, Leng Shuguang, Duan Huawei*, Zheng Yuxin*. Ambient particulate matter compositions and increased oxidative stress: Exposure-response analysis among high-level exposed population. Environment international, 2021, 147: 106341
18.Jiang Qixiao, Xu Xiaohui, DeWitt Jamie C., Zheng Yuxin*. Using Chicken Embryo as a Powerful Tool in Assessment of Developmental Cardiotoxicities. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2021, 169: e62189
19.Zhao Yanjie, Zhang Heng, Ju Qiang, Li Xinmei, Zheng Yuxin*. Comprehensive Analysis of Survival-Related lncRNAs, miRNAs, and mRNAs Forming a Competing Endogenous RNA Network in Gastric Cancer. Frontiers in genetics, 2021, 12: 610501
20.Jiang Menghui, Li Daochuan, Piao Jinmei, Li Yanting, Chen Liping, Li Jianyu, Yu Dianke, Pi Jingbo, Zhang Rong, Chen Rui, Chen Wen, Zheng Yuxin*. Nrf2 modulated the restriction of lung function via impairment of intrinsic autophagy upon real-ambient PM2.5 exposure. Journal of Hazardous Materials, 2021, 408, 124903.
21.Wang Tao, Zhou Yunping, Kong Nan, Zhang Jianzhong, Cheng Guo, Zheng Yuxin*. Weight gain from early to middle adulthood increases the risk of incident asthma later in life in the United States: a retrospective cohort study. Respir Res. 2021, 22(1):139.
22.Kong Nan, Chen Guoshun, Wang Haitao, Li Jianyu, Yin Shuzhen, Cao Xue, Wang Tao, Li Xin, Li Yanan, Zhang Huanling, Yu Shanfa, Tang Jinglong, Sood Akshay, Zheng Yuxin*, Leng Shuguang*. Blood leukocyte count as a systemic inflammatory biomarker associated with a more rapid spirometric decline in a large cohort of iron and steel industry workers. Respir Res. 2021, 22(1): 254.
23.Wang Tao, Li Jianyu, Liang Yi, Han Wei, Tang Jinglong, Cheng Guo and Zheng Yuxin*. Joint Effects of Carbon Black Exposure and Dietary Antioxidant Vitamin Intake on Small Airway Dysfunction. Front. Nutr. 2021, 8:716398.
24.Liu H, Li J, Ma Q, Tang J, Jiang M, Cao X, Lin L, Kong N, Yu S, Sood A, Zheng Y*, Leng S*, Han W*. Chronic exposure to diesel exhaust may cause small airway wall thickening without lumen narrowing: a quantitative computerized tomography study in Chinese diesel engine testers. Part Fibre Toxicol. 2021 Mar 25;18(1):14.
三、主要科研项目
1. 新能源产业重要职业性有害因素的健康效应与毒性机制研究，国家自然科学基金专项项目，200万，2023/01-2026/12，主持
2. 大气细颗粒物健康危害的系统毒理学与系统流行病学研究，国家自然科学基金重大研究计划集成项目，200万，2020.1-2022.12，参与
3. 基于人群队列的食品污染物生物标志物研究与应用，科技部重点研发计划，369万，2018.01-2021.12，主持
4. 交通尾气颗粒物致健康损害效应的关键组分及人群生物标志物研究，国家自然科学基金重大研究计划重点支持项目，296万，2017.1-2020.12，主持5. 预防医学学科发展战略研究项目，国家自然科学基金应急管理项目，10万， 2019.1-2019.12，主持
四、主要科学技术奖励
1. 中华预防医学一等奖，2021年
2.十一五国家科技计划执行突出贡献奖 ，2011
3. 中华预防医学二等奖，2009年
4. 中华预防医学二等奖， 2007年5. 国家质量监督检验检疫总局科技兴检奖三等奖，2005年
五、联系方式
邮箱：yxzheng@qdu.edu.cn
