张林

来源:必赢线路检测3003no1 发布时间:2023-07-20 15:31:37

40713

  张林,医学博士,博士后,研究员,博士研究生导师,山东省泰山学者青年专家,齐鲁卫生与健康杰出青年人才。2018年博士毕业于郑州大学劳动卫生与环境卫生学专业,现担任山东省妇幼保健院妇女儿童疾病临床医学研究中心主任,受聘Military Medical Research科学编辑、中华预防医学会煤炭系统分会委员、中国毒理学会免疫毒理学专业委员会委员、中国环境诱变剂学会生物标志物专业委员会青年委员。主持国家自然科学基金重点项目子课题1项、国家自然科学基金青年基金1项、山东省自然科学基金1项,横向课题多项,在国内外学术期刊发表高水平论文20余篇。

  主要研究方向:

  1. 环境生殖和发育毒理学;

  2. 妇幼临床流行病学;

  3. 职业性呼吸系统发生机制和现场研究。

二、代表性科研成果

1. Zhang L, Tian J, Ma L, Duan S. Mechanistic insights into severe pulmonary inflammation caused by silica stimulation: The role of macrophage pyroptosis. Ecotoxicology and Environmental Safety. 2023 Jun 15;258:114975.

2. Yin H, Fang L, Wang L, Xia Y, Tian J, Ma L, Zhang J, Li N, Li W, Yao S, L Z. Acute Silica Exposure Triggers Pulmonary Inflammation Through Macrophage Pyroptosis: An Experimental Simulation. Front Immunol 2022, 13: 874459.

3. Wang L, Fang L, Fang Z, Zhang M, Zhang L. Assessment of the association between prenatal exposure to multiple ambient pollutants and preterm birth: A prospective cohort study in Jinan, east China. Ecotoxicol Environ Saf 2022, 232: 113297.

4. Yin H, Li J, Tian J, Ma L, Zhang J, Zhai Q, Yao S, Zhang L. Uterine pyruvate metabolic disorder induced by silica nanoparticles act through the pentose phosphate pathway. J Hazard Mater 2021, 412: 125234.

5. Ma L, Han Z, Yin H, Tian J, Zhang J, Li N, Ding C, Zhang L. Characterization of cathepsin B in mediating silica nanoparticle-induced macrophage pyroptosis via an NLRP3-dependent manner. Journal of Inflammation Research. 2022 Jan 1:4537-45.

6. Duan S, Zhang M, Li J, Tian J, Yin H, Wang X, Zhang L. Uterine metabolic disorder induced by silica nanoparticles: biodistribution and bioactivity revealed by labeling with FITC. J Nanobiotechnology 2021, 19(1): 62.

7. Zheng C, Tian J, Ma L, Ding C, Zhang L. Association between prenatal exposure to ambient ozone, birth weight, and macrosomia in healthy women. Front Public Health 2022, 10: 1000269.

8. Wei D, Liu JY, Sun Y, Shi Y, Zhang B, Liu JQ, Tan J, Liang X, Cao Y, Wang Z, Qin Y, Zhao H, Zhou Y, Ren H, Hao G, Ling X, Zhao J, Zhang Y, Qi X, Zhang L, Deng X, Chen X, Zhu Y, Wang X, Tian LF, Lv Q, Ma X, Zhang H, Legro RS, Chen ZJ. Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial. Lancet 2019, 393(10178): 1310-1318.

9. Shi Y, Sun Y, Hao C, Zhang H, Wei D, Zhang Y, Zhu Y, Deng X, Qi X, Li H, Ma X, Ren H, Wang Y, Zhang D, Wang B, Liu F, Wu Q, Wang Z, Bai H, Li Y, Zhou Y, Sun M, Liu H, Li J, Zhang L, Chen X, Zhang S, Sun X, Legro RS, Chen ZJ. Transfer of Fresh versus Frozen Embryos in Ovulatory Women. N Engl J Med 2018, 378(2): 126-136.

三、主要科研和人才项目

1、国家自然科学基金青年项目,82003405,2021.01-2023.12,1/1,30万元

2、山东省自然科学基金青年项目,ZR2020QH290,2021.01-2023.12,1/1,15万元

3、山东省泰山学者青年专家项目,2022.07-2025.06,1/1,180万元

4、齐鲁卫生与健康杰青人才计划,2021.01-2025.12,1/1,80万元

5、国家卫健委生育药具重点实验室,2021KF03,2021.10-2023.9,1/6,7.5万元

6、河南省创伤与骨科研究医学重点实验室,HZKFKT20220502,2022.06-2024.05,1/10,50万元

7、国家自然科学基金重点项目,U1904209,2020.01-2023.12,4/10,218万元

E-mail:zhanglin8901@sdu.edu.cn,办公电话:0531-68795920

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